Clinical trials offer an opportunity for patients to participate in scientific and industry research. In a clinical trial, participants receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices, procedures, or changes to participants’ behavior, such as diet.
Clinical Trial Participation – Patient Considerations
Skip forward on this page to read and understand more about clinical trial participation.
National Institutes of Health PSC Trials
The National Institutes of Health (NIH) offers a web site of clinical trials specific to PSC. You can visit the site by clicking here.
At this time the following research trials are recruiting participants who have been diagnosed with PSC. These trials may or may not be related to the NIH trials. The trials are listed in order by most to least recent announcement.
DUR-928 Safety and Efficacy Trial for Adults with PSC
GS-9674 Safety and Efficacy Trial for Adults with PSC
Obeticholic Acid in PSC
Genomics of Primary Sclerosing Cholangitis
PSC with Oral Vancomycin
PSC Study at University of California/Davis
Noninvasive Assessment of Disease Progression in Primary Sclerosing Cholangitis
What should a patient consider before enrolling in a clinical study?
Christopher L. Bowlus, MD, University of California Davis, Co-Chair, PSC Partners Scientific/Medical Advisory Committee
Participating in clinical studies is critical to understanding PSC and to developing effective treatments. The opportunities for PSC patients to participate in studies has increased significantly in the last decade and hopefully will continue to increase as we make progress towards improving the lives of PSC patients. Although there are unique challenges to PSC given its rarity and the slow and variable progression of the disease, the general rules and ethics of conducting clinical studies are the same as in any other disease. The following are some general principles to consider before participating in a clinical study.